LIPOPEPTIDES FROM ACTINOPLANES SP. WITH PHARMACOLOGICAL ACTION, PROCESS FOR THEIR PRODUCTION AND THE USE THEREOF

摘要

Lipopeptides from Actinoplanes sp. with pharmacological action, process for their production and the use thereof The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actino-planes sp. during fermentation and are released into the culture medium, to a process for isolating the lipopeptides from the culture medium cad purifying theme, to the use of the lipopeptides as pharmacologically active substances, in particular against Gram-positive bacteria, and to Actinoplaaes sp. DSM 7358 for producing the abovementioned lipopeptides.