发明名称 Cell membrane fusion composition and method
摘要 A lipid vesicle composition for use in delivering a vesicle-encapsulated agent to a target cell is disclosed. The composition is formed of vesicle-forming lipids, including at least 10 mole percent plasmalogen phospholipid with a small-volume polar head group. The composition may also include a fusion protein for promoting fusion of the vesicles to the target cells. A novel fusion protein identified as an isoform of glyceraldehyde-3-phosphate dehydrogenase is also disclosed.
申请公布号 US6099857(A) 申请公布日期 2000.08.08
申请号 US19980092617 申请日期 1998.06.05
申请人 WASHINGTON UNIVERSITY 发明人 GROSS, RICHARD W.
分类号 A61K9/127;C12N9/02;(IPC1-7):A61K9/127;A61K9/133 主分类号 A61K9/127
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