| 发明名称 |
Hydroxamic and carboxylic acid derivatives |
| 摘要 |
For the treatment of cancer, inflammation, and other conditions associated with matrix metalloproteinases or that are mediated by TNF alpha or enzymes involved in the shedding of L-selectin, CD23, the TNF receptors, IL-1 receptors, or IL-6 receptors, disclosed are compounds of the general formula B-X-(CH2)m-(CR1R2)n-W-COY.
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| 申请公布号 |
US6100266(A) |
申请公布日期 |
2000.08.08 |
| 申请号 |
US19990239603 |
申请日期 |
1999.01.29 |
| 申请人 |
DARWIN DISCOVERY LIMITED |
发明人 |
MONTANA, JOHN GARY;BAXTER, ANDREW DOUGLAS;OWEN, DAVID ALAN |
| 分类号 |
C07D295/22;A61K31/19;A61K31/192;A61K31/495;A61P1/02;A61P1/04;A61P1/14;A61P7/02;A61P7/04;A61P9/00;A61P9/08;A61P9/10;A61P11/06;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/06;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P31/00;A61P35/00;A61P35/04;A61P37/06;C07C;C07C317/44;C07C317/46;(IPC1-7):A61K31/495;A61K31/455;A61K31/44;A61K31/38 |
主分类号 |
C07D295/22 |
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