| 摘要 |
PROBLEM TO BE SOLVED: To obtain a polypeptide hat include an SOD-like polypeptide having a prescribed molecule and a specific amino acid sequence, thus can induce the prevention against the pathogenic action of inducing Eimeria infection in poultry and is useful for producing vaccine and the like. SOLUTION: This is a hydrophilic Eimeria polypeptide isolated from Eimeriatenella or the like. The polypeptide is an SOD-like polypeptide, has a molecular weight of 25 kD and include and amino acid sequence having >=70% homology to that of the formula I or a peroxidoxin-like polypeptide with a 22 kD molecular weight and >=70% homology to that of formula II. In a preferred embodiment, this polypeptide is mixed with a pharmaceutically acceptable support to produce the vaccine for the Eimeria infections. In another case, the polypeptide is given to a suitable animal to produce the antibody against the polypeptide. |
