| 摘要 |
A method of purifying 1alpha-hydroxyvitamin D2 to obtain 1alpha-hydroxyvitamin D2 in crystalline form. The method includes the steps of boiling a solvent selected from the group consisting of ethyl formate, ethyl acetate and a 2-propanol-hexane mixture under inert atmosphere, dissolving a product containing 1alpha-hydroxyvitamin D2 to be purified in the. solvent, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of 1alpha-hydroxyvitamin D2 crystals, and recovering the 1alpha-hydroxyvitamin D2 crystals. Optionally, petroleum ether may be added to the solvent after dissolving the product to be purified in the solvent. |
