AMELIORANT FOR HEPATITIS C REMEDIAL EFFECT AND APPLICATION THEREOF

摘要

The present invention provides an ameliorant for enhancing the therapeutic effect of IFN- alpha on hepatitis C; a therapeutic composition for the treatment of hepatitis C which comprises IFN- alpha and IFN- gamma as active ingredients and further contains a pharmaceutically acceptable carrier; a kit for the treatment of hepatitis C which comprises an IFN- alpha preparation and an IFN- gamma preparation; and a therapeutic method for the treatment of hepatitis C which comprises administering IFN- alpha and IFN- gamma to a subject at the same time or administering IFN- gamma before the administration of IFN- alpha . The present invention is capable of making the patient continuously HCV-RNA negative and is extremely useful in the treatment of chronic hepatitis C which is intractable with IFN- alpha and conventionally difficult to remedy.