A genetic test for alpha-mannosidosis

摘要

A method for diagnosing or screening for bovine alpha-mannosidosis comprises detecting in nucleic acid samples from cattle the presence or absence of alpha-mannosidosis-causing mutations in the gene encoding bovine lysosomal alpha-mannosidase (LAMAN). A method of detecting alpha-mannosidosis-causing mutations in cattle comprises detecting the presence or absence of base transitions in the gene encoding bovine LAMAN which are associated with the disease.