发明名称 Process for preparing chromanol derivatives
摘要 A process for preparing chromanol derivatives of the formula I where n is from 1 to 10, R1, R2, R3, R4 independently of one another are hydrogen or C1-C4 alkyl, R5 is hydrogen, C1-C4 alkyl, C6-C10 aryl, C7-C18 aralkyl, C7-C18 alkylaryl, C1-C22 acyl, or a group protecting the hydroxyl, by reduction of the corresponding 4-oxochromanol derivatives of the formula II comprises reacting the 4-oxochromanol derivatives of the formula II with metallic zinc in the presence of an acid or an acid mixture. Compounds of the formula I having C1-C22 acyl as radical R5 can also be prepared by the above-described reduction of the compounds of the formula II with hydrogen as radical R5 and simultaneous or subsequent esterification.
申请公布号 US6096907(A) 申请公布日期 2000.08.01
申请号 US19990395774 申请日期 1999.09.14
申请人 BASF AKTIENGESELLSCAHFT 发明人 BALDENIUS, KAI-UWE;BOCKSTIEGEL, BERNHARD;JAEDICKE, HAGEN;RUFF, DETLEF;SIEDENBIEDEL, CARSTEN;STUERMER, RAINER
分类号 C07D311/70;C07D311/72;(IPC1-7):C07D311/76 主分类号 C07D311/70
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