发明名称 |
Liposome-mediated transfection of central nervous system cells |
摘要 |
Disclosed are methods for use in transferring nucleic acids into central nervous system cells in vivo and in vitro and/or for stimulating central nervous system cells. Neurotrophic genes are shown to stimulate neurofilament cells and to promote nerve cell growth, repair and regeneration in vivo. Gene transfer protocols are disclosed for use in transferring various nucleic acid materials into central nervous system cells, as may be used in treating various pathologies of the brain and spinal cord.
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申请公布号 |
US6096716(A) |
申请公布日期 |
2000.08.01 |
申请号 |
US19940353901 |
申请日期 |
1994.12.12 |
申请人 |
THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
HAYES, RONALD L.;YANG, KEYI;FAUSTINELLA, FABRIZIA |
分类号 |
A61K9/127;A61K38/00;C07K14/475;C07K14/48;C12N15/88;(IPC1-7):A01N43/04;A61K31/70;C12N15/63 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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