发明名称 |
Method for treating wounds using modified hyaluronic acid crosslinked with biscarbodiimide |
摘要 |
This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.
|
申请公布号 |
US6096727(A) |
申请公布日期 |
2000.08.01 |
申请号 |
US19980028414 |
申请日期 |
1998.02.24 |
申请人 |
ANIKA THERAPEUTICS, INC.;RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
KUO, JING-WEN;SWANN, DAVID A.;PRESTWICH, GLENN D. |
分类号 |
A61K9/00;A61K47/36;A61K47/48;A61L15/28;A61L27/20;A61L31/04;C08B37/08;(IPC1-7):A61K31/715 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|