Novel azalides and methods of making same

摘要

This invention relates to methods of preparing compounds of Formula 1: and to pharmaceutically acceptable salts and solvates thereof, and to methods for preparing same. The compounds of Formula 1 are antibacterial agents that may be used to treat various bacterial and protozoal infections, and may also be used to treat cancer. The invention also relates to pharmaceutical compositions comprising the compounds of Formula 1, and to methods of treating bacterial and protozoal infections by administering compounds of Formula 1.