发明名称 |
ACRIDONE-DERIVED BISINTERCALATORS AS CHEMOTHERAPEUTIC AGENTS |
摘要 |
<p>The present invention provides an anticancer compound having the structure: <IMAGE> +TR <IMAGE>independently -H, -OH, -NH2, -OCH3, -C(CH3)3, or a halogen atom; n is 2 to 6; X and X' are independently -N or -NO2; Y and Y' are independently -N, -CH, or -H; and the double-slash represents a double bond or no bond; such that when X or X' is -N, Y or Y' is -CH or -N, and the double-slash is a double bond, and when X or X' is -NO2, Y or Y' is -H, and the double-slash is no bond. The present invention also provides a pharmaceutical composition comprising the compound above and a pharmaceutically acceptable carrier.</p> |
申请公布号 |
GR3032836(T3) |
申请公布日期 |
2000.07.31 |
申请号 |
GR20000400528T |
申请日期 |
2000.02.29 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
MICHEJDA, CHRISTOPHER, J.;CHOLODY, WIESLAW, M.;HERNANDEZ, LIDIA |
分类号 |
G01N33/50;A61K31/435;A61K31/47;A61K31/473;A61K49/00;A61P35/02;C07D219/06;C07D219/08;C07D471/06;C07D519/00;C07H21/00;(IPC1-7):C07D219/08;C12Q1/68 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|