发明名称 Improved formulation for topical non-invasive application in vivo
摘要 A formulation comprising molecular arrangements capable of penetrating pores in a barrier, owing to penetrant adaptability, despite the fact that the average diameter of said pores is smaller than the average penetrant diameter, provided that the prenetrants can transport agents or else enable agent permeation through the pores after penetrants have entered pores, characterized in that the formulation comprises at least one consistency builder in an amount that increases the formulation to maximally 5 Nm/s so that spreading over, and retention at, the application area is enabled and/or at least one antioxidant in an amount that reduces the increase of oxidation index to less than 100% per 6 months and/or at least one microbiocide in an amount that reduces the bacterial count of 1 million germs added per g of total mass of the formulation to less than 100 in the case of aerobic bacteria, to less than 10 in the case of entero-bacteria, and to less than 1 in the case of Pseudomonas aeruginosa or Staphilococcus aureus, after a period of 4 days.
申请公布号 AU2513799(A) 申请公布日期 2000.07.31
申请号 AU19990025137 申请日期 1998.12.23
申请人 IDEA INNOVATIVE DERMALE APPLIKATIONEN GMBH 发明人 GREGOR CEVC
分类号 A61K9/10;A61K9/127;A61K31/16;A61K31/56;A61K31/57;A61K31/58;A61K47/02;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/22;A61K47/24;A61K47/26;A61K47/28;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61K47/46;A61P1/16;A61P1/18;A61P7/06;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P17/14;A61P19/00;A61P19/02;A61P21/00;A61P25/08;A61P27/00;A61P27/02;A61P29/00;A61P31/12;A61P31/22 主分类号 A61K9/10
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