发明名称 |
COMPOUNDS BELONGING TO THE D-VITAMINS GROUP AND METHOD OF OBTAINING THEM |
摘要 |
<p>The invention relates to a vitamin D compound of the general formula <CHEM> wherein: R1 is a hydrogen atom or a hydroxy protecting group; Z is a group of the general formula <CHEM> wherein R2 and R3 are each individually straight or branched, substituted or unsubstituted, (C1-C6)alkyl groups, (C2-C6)alkenyl groups, (C3-C6)cycloalkyl groups or phenyl groups; or wherein R1 and R3 together with the interconnecting oxadimethylene biradical form a 5-7 membered ring-closed (C1-C4)alkyl substituted hemiacetal; with the proviso, that R2 and R3 are not both or individually methyl groups; A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention also relates to a method of preparing these compounds and to their use in pharmacology. The invention further relates to valuable new intermediates.</p> |
申请公布号 |
PL179063(B1) |
申请公布日期 |
2000.07.31 |
申请号 |
PL19950306849 |
申请日期 |
1995.01.17 |
申请人 |
DUPHAR INTERNATIONAL RESEARCH BV. |
发明人 |
TORNEIRO MERCEDES;FALL YAGAMARE;MOURINO ANTONIO;ZORGDRAGER JAN;VAN DE VELDE JEAN-PAUL |
分类号 |
A61K31/59;A61P3/02;A61P11/06;A61P17/00;A61P19/00;A61P35/00;C07C;C07C401/00;C07D309/12;C07D317/20;C07F7/18;C07F9/117;(IPC1-7):C07C401/00 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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