摘要 |
A compound of the formula (I): <CHEM> wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is COOR<A> wherein R<A> is hydrogen or ester residue, -CONR<B>R<C> wherein R<B> and R<C> each is independently hydrogen or amide residue, optionally substituted aryl or optionally substituted heteroaryl; and A<1> is optionally substituted heteroaryl; provided that a compound wherein Y and/or A<1> is optionally substituted indol-3-yl is excluded, a tautomer, a prodrug, a pharmaceutically acceptable salt or a hydrate thereof has an inhibitory activity against an integrase. |