发明名称 AZA SPIRO COMPOUNDS AND COMPOSITION ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY
摘要 The invention relates to spiro compounds having central and peripheral nervous system activity, for example muscarinic agonist activity, having formulas wherein their pharmaceutically acceptable salts, quaternary compounds which are structurally derived said compounds having a tertiary nitrogen atom, enantiomers and racemates, wherein A together with the spiro-carbon atom constitutes a bridged or unbridged ring containing one or two ring nitrogen atoms, and the value of each of the other symbols in the formulae is defined. 10 claims
申请公布号 BG62774(B1) 申请公布日期 2000.07.31
申请号 BG19960100370 申请日期 1996.02.19
申请人 STATE OF ISRAEL REPRESENTED BY THE PRIME MINISTER'SOFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH 发明人 FISHER, ABRAHAM;KARTON, YISHAL;MARCIANO, DANIELE;BARAK, DOV;MESHULAM, HAIM
分类号 C07D487/10;A61K31/42;A61K31/425;A61K31/435;A61K31/438;A61P25/00;A61P25/04;A61P25/18;A61P25/28;C07D453/02;C07D471/10;C07D471/20;C07D491/10;C07D497/10;C07D498/10;C07D498/20;C07D513/10;(IPC1-7):C07D471/10 主分类号 C07D487/10
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