发明名称 |
AZA SPIRO COMPOUNDS AND COMPOSITION ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY |
摘要 |
The invention relates to spiro compounds having central and peripheral nervous system activity, for example muscarinic agonist activity, having formulas wherein their pharmaceutically acceptable salts, quaternary compounds which are structurally derived said compounds having a tertiary nitrogen atom, enantiomers and racemates, wherein A together with the spiro-carbon atom constitutes a bridged or unbridged ring containing one or two ring nitrogen atoms, and the value of each of the other symbols in the formulae is defined. 10 claims
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申请公布号 |
BG62774(B1) |
申请公布日期 |
2000.07.31 |
申请号 |
BG19960100370 |
申请日期 |
1996.02.19 |
申请人 |
STATE OF ISRAEL REPRESENTED BY THE PRIME MINISTER'SOFFICE ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH |
发明人 |
FISHER, ABRAHAM;KARTON, YISHAL;MARCIANO, DANIELE;BARAK, DOV;MESHULAM, HAIM |
分类号 |
C07D487/10;A61K31/42;A61K31/425;A61K31/435;A61K31/438;A61P25/00;A61P25/04;A61P25/18;A61P25/28;C07D453/02;C07D471/10;C07D471/20;C07D491/10;C07D497/10;C07D498/10;C07D498/20;C07D513/10;(IPC1-7):C07D471/10 |
主分类号 |
C07D487/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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