发明名称 Phenazine compounds, methods and pharmaceutical compositions for inhibiting parp
摘要 This invention relates to compounds, pharmaceutical compositions, and methods of using compounds of the formula:wherein R1-R9 and Z are independently. hydrogen, hydroxy, halo, haloalkyl, thiocarbonyl, cyano, nitro, amino, imino, alkylamino, aminoalkyl, sulfhydryl, thioalkyl, alkylthio, sulfonyl, alkylsulfonyl, C1-C9 straight or branched chain alkyl, C2-C9 straight or branched chain alkenyl, C2-C9 straight or branched chain alkynyl, C1-C6 straight or branched chain alkoxy, C2-C6 straight or branched chain alkenoxy, C2-C6 straight or branched chain alkynoxy, aryl, carbocycle, heterocycle, aralkyl, alkylaryl, alkylaryloxy, aryloxy, aralkyloxy, aralkylsulfonyl, aralkylamino, arylamino, arylazo, arylthio, or aralkylthio; or Z iswherein U is C or N, and R7 and R8 are defined above; and X and Y are independently aryl, carbocycle, or heterocycle.
申请公布号 AU2217400(A) 申请公布日期 2000.07.31
申请号 AU20000022174 申请日期 1999.12.28
申请人 GUILFORD PHARMACEUTICALS INC. 发明人 JIE ZHANG;KEVIN LEONARD TAYS;JIA-HE LI
分类号 A61P39/00;C07D241/46;C07D405/12;C07D417/12 主分类号 A61P39/00
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