发明名称 |
Pharmaceutical formulation containing a microbial enzyme which digests hyaluronic acid |
摘要 |
The invention relates to pharmaceutical compositions which are especially suitable as injection preparations to be used for the therapy of vascular diseases which are caused by atheromatous deposits on the inner walls of arteria. Said injection preparations contain bacterial hyaluronate lyase or a hyaluronate-digesting enzyme fragment produced from said enzyme. The invention also relates to the hyaluronate-digesting enzyme fragment of the bacterial hyaluronate lyase. It may be produced by treating the holoenzyme with a specifically digesting protease. |
申请公布号 |
AU3032400(A) |
申请公布日期 |
2000.07.31 |
申请号 |
AU20000030324 |
申请日期 |
1999.12.22 |
申请人 |
ID-PHARMA GMBH;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;NORBERT PRESSELT |
发明人 |
NORBERT PRESSELT;PETER-JURGEN MULLER;JORG-HERMANN OZEGOWSKI;ALBERT HARTL;GUNDELA PESCHEL |
分类号 |
A61K9/08;A61K38/00;A61K38/51;A61K47/02;A61K47/26;A61P7/02;A61P9/06;A61P9/10;C12N9/88 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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