A method of treating harmful effects of an endogenous HGF using a modified HGf which in non-glycosylated

摘要

This use of a modified HGF (haemopoietic growth factor) is in medicaments for ameliorating the aberrant effects of an endogenous HGF in a mammal. The modified HGF used is characterised by being in an unglycosylated form and comprising a sequence of amino acids within a first a-helix where one of the amino acids having acidic properties is substituted with a basic amino acid residue.