发明名称 |
Aminoguanidine carboxylates useful for the treatment of non-insulin dependent diabetes mellitus |
摘要 |
The compound has the formula I AG-(CH2)n-CO2R1 wherein one of the hydrogens of (CH2)n can be replaced by R2; AG is N-aminoguanidine, N,N'-di-aminoguanidine or N,N',N"-tri-aminoguanidine; n is 1 to 5; R1 is H, phenyl, alkyl or alkyl-phenyl and R2 is phenyl, alkyl or alkyl-phenyl limited by the provisos listed in the specification. The compound is useful for treating or preventing non-insulin dependent diabetes mellitus or obesity.
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申请公布号 |
NZ297604(A) |
申请公布日期 |
2000.07.28 |
申请号 |
NZ19950297604 |
申请日期 |
1995.11.13 |
申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
LARSEN, SCOTT D;VAILLANCOURT, VALERIE A;MAY, PAUL D;TANIS, STEVEN P;TUCKER, JOHN A;MEGLASSON, MARTIN D;SCHOSTAREZ, HEINRICH J |
分类号 |
A61K31/195;A61K31/198;A61K31/215;A61P3/08;A61P3/10;C07C281/16;C07C281/18;(IPC1-7):C07C281/18;C07D281/16 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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