Pyridazino(4,5-b)indole-1-acetamide compounds have an affinity for peripheral benzodiazepine receptors for treating central nervous system degenerative disorders, cardiac disorders, nephropathies, and the like

摘要

Pyridazino(4,5-b)indole-1-acetamide derivatives (I) are used in medicines for preventing and treating disorders due to dysfunction of peripheral benzodiazepine receptors. Pyridazino(4,5-b)indole-1-acetamide derivatives of formula (I) are used in medicines for preventing and treating disorders due to dysfunction of peripheral benzodiazepine receptors. X = halo; Y' = H, halo, OH, methyl, methoxy or nitro; R1 = 1-4C alkyl; R2, R3 = H, 1-4C alkyl, or, together with the N atom, form pyrrolidinyl, piperidinyl or morpholinyl.