Radiopharmaceutical comprising technetium or rhenium, a biologically active group, a first ancillary ligand, and a second stabilising

摘要

Radiopharmaceutical complexes used as imaging agents for the diagnosis of cardiovascular disorders, infectious diseases like cancer. The radiopharmaceuticals are comprised a transition metal radionuclide, transition metal chelator, biologically active group connected to the chelator, first ancillary ligand, second ancillary ligand capable of stabilising the radiopharmaceutical, optionally having a linking group between the chelator and active group that selectively localize at sites of disease and allow an image to be obtained of the loci using gamma scintigraphy. Further disclosed is a kit and method of radioimaging.