发明名称 METHOD FOR IDENTIFYING THE LIGANDS OF A RECEPTOR CAPABLE OF BEING INTERNALIZED
摘要 <p>The invention concerns a method useful for detecting and/or identifying in a bank of peptides, pseudopeptides and non-peptide compounds, a biological extract or a purified fraction of a tissue extract, a ligand of a receptor of interest capable of being subjected to internalization induced by immobilising said ligand. The invention is characterised in that it comprises at least steps which consist in: expressing at the surface of a cell said receptor in a marked form; bringing in contact said cell and said bank in conditions suitable for cell internalization of said ligand-receptor complex; and displaying said internalization via the detection of the marker associated with said receptor.</p>
申请公布号 WO2000043779(A1) 申请公布日期 2000.07.27
申请号 FR2000000113 申请日期 2000.01.19
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