| 发明名称 |
IONIC MOLECULAR CONJUGATES OF BIODEGRADABLE POLYESTERS AND BIOACTIVE POLYPEPTIDES |
| 摘要 |
Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50 % by weight of the polypeptide present in the compositio n is ionically conjugated to the polyester.
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| 申请公布号 |
CA2358829(A1) |
申请公布日期 |
2000.07.27 |
| 申请号 |
CA20002358829 |
申请日期 |
2000.01.26 |
| 申请人 |
POLY-MED, INC.;SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. |
发明人 |
SHALABY, SHALABY W.;JACKSON, STEVEN A.;MOREAU, JACQUES-PIERRE |
| 分类号 |
A61K38/00;A61K9/52;A61K38/04;A61K38/22;A61K38/27;A61K47/48;A61P35/00;A61P43/00;C07K7/23;C07K14/47;C07K14/59;C07K14/655;C07K19/00;C08G63/00;C08G63/06;C08G63/08;C08G63/64;C08G63/91;C08G81/00;C08J5/00;C08J7/04;C08L67/00;C08L101/16;(IPC1-7):C08G63/08 |
主分类号 |
A61K38/00 |
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