| 摘要 |
Compounds having an antitumor activity and causing no morphological change in cells. Compounds of general formula (I), pharmaceutically acceptable salts of them and solvates thereof, and medicinal compositions containing the same. In formula (1), X and Z represent each CH or N; R<1-3> represent each H, optionally substituted alkoxy, etc.; R<4> represents H; R<5-8> represent each H, halogeno, alkyl, alkoxy, alkylthio, nitro or amino, provided that all of R<5-8> do not represent H simultaneously; R<9> and R<10> represent each H, alkyl or alkylcarbonyl; and R<11> represents alkyl, alkenyl, alkynyl or aralkyl.
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