| 摘要 |
A method and an apparatus are provided for delivery of radiation in vivo. A device includes a seal located proximal to a balloon through which a cavity of the balloon is inflated with a composition including a radioactive compound. Preferably, the seal includes a first passage provides access for the inflation tubing through the seal which, at the distal end, terminates at a location within the balloon cavity. A second passage, also included in the seal, provides access for the flushing tubing which, at the distal end, terminates at the proximal end of the balloon. These passages through the seal isolate the radioactive material source from a flushing mechanism. In such a construction, inflation and evacuation can be accomplished without contamination of the entire medical device lumen. Thus, substantially all of the solution including the radioactive compound can be evacuated and the balloon cavity can be subsequently flushed or rinsed to remove substantially all the radioactive compound after treatment due to the positioning of the passage in the seal.
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