发明名称 TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES
摘要 PURPOSE: A synthetic process for novel bicyclic tris(anhydride)s useful as intermediates in the synthesis of biologically active compounds, and the compounds which may be synthesized from such intermediates, is provided. CONSTITUTION: A compound having the following structure is provided, wherein Z and Z1 are the same or different and are alkyl, aralkyl, aryl, aminoalkyl, alkyloxy, aralkyloxy, alkylamino, aralkylamino, arylamino, alkylmercaptan, aralkylmercaptan, arylmercaptan, carbohydrate, nucleoside, steroid, or substituted glyceride; and X is methylene (-CH2-), mono- or di-halo methylene, or -NR-, where R is H or alkyl.
申请公布号 KR20000049026(A) 申请公布日期 2000.07.25
申请号 KR19997003092 申请日期 1999.04.09
申请人 PHARMASSET, LTD. 发明人 PANKIEWICZ KRZYSZTOF W.;LESIAK KRYSTYNA;WATANABE KYOICHI A.
分类号 A61K31/7076;A61K31/708;A61P35/02;A61P43/00;C07F9/09;C07F9/165;C07F9/24;C07F9/32;C07F9/40;C07F9/44;C07F9/6568;C07F9/6571;C07F9/6581;C07H19/10;C07H19/20;C07H19/207;(IPC1-7):C07F9/32 主分类号 A61K31/7076
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