| 摘要 |
PURPOSE: Monocyclic l-nucleosides, analogs and uses thereof are provided, and compounds thereof represented by Formula I may be used to treat an infection, an infestation, a cancer or tumor or an autoimmune disease. CONSTITUTION: Novel monocyclic L-nucleoside compounds have general formula (I). Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in terms of mechanism, embodiments of the novel compounds show immunomodulatory activity, and are expected to be useful in modulating the cytokine pattern, including modulation of Th1 and Th2 response.
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