PROCESS FOR PREPARING FLUOR CONTAINING PHENETHYLAMINES AND FLOUR CONTAINING BETA-IMINOVINYL- AND BETA-IMINOETHYLPHENYL COMPOUNDS

摘要

PURPOSE: A production process of phenethylamines containing fluor is provided which comprises 3 steps to get more than 80% yield. CONSTITUTION: A production process of phenethylamines containing fluor is characterized by comprising steps of: (i) a first step wherein substituted bromobenzene is reacted with N-vinyl amide in the presence of palladium catalyst; (ii) a second step wherein the produced β-iminoethyl benzene is hydrogenated; and (iii) a third step wherein the substituted β-iminoethyl benzene as shown in a chemical formula 2 is decomposed to produce phenethylamines containing fluor as shown in a chemical formula 1.