DNA encoding the T cell surface protein T4 and use of fragments of T4 in the treatment of AIDS
摘要
This invention provides an isolated single-stranded nucleic acid which encodes an aqueous-soluble polypeptide comprising at least a portion of a human T4 glycoprotein, which portion specifically forms a complex with a human immunodeficiency virus envelope glycoprotein.
申请公布号
US6093539(A)
申请公布日期
2000.07.25
申请号
US19950466368
申请日期
1995.06.06
申请人
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人
MADDON, PAUL J.;LITTMAN, DAN R.;CHESS, LEONARD;AXEL, RICHARD;WEISS, ROBIN;MCDOUGAL, J. STEVEN