COMPOSITION FOR ORAL ADMINISTRATION COMPRISING ACEGLUTAMIDE ALUMINUM AND CARAGEENAN

摘要

PURPOSE: A composition for oral administration comprising aceglutamide aluminum and carageenan is provided so that patients take medicine easily by removing bitterness and astringent taste of aceglutamide aluminum without any further costs and stability of the composition is improved in aqueous solution or suspension. CONSTITUTION: Aceglutamide aluminum (pentakis (N¬2-acetyl-L-glutaminato) tetrahydroxytri-aluminum, C35H59A13N10O24) is useful as an anti-ulcerative agent. Carageenan is a high molecular weight of polymer isolated from collagen, and is used for removing bitterness and astringent taste of aceglutamide aluminum and for stabilizing the same physiologically in being formulated in the form of aqueous solution or suspension by inhibiting the phase-separation. The composition comprises 1 to 30 wt % of aceglutamide aluminum and 0.01 to 10 wt % of carageenan.