发明名称 RAS ACTIVATOR NUCLEIC ACID MOLECULES, PROTEINS AND METHODS OF USE
摘要 The invention is a RasGRF4 nucleic acid molecule and its corresponding protein which has an important role in cell signaling. This protein is regulated by Nedd4, which regulates protein stability, PDZ, which localizes the protein, and cNMP which activates it. The invention also includes biologically functional equivalent nucleic acid molecules and proteins. The invention also relates to methods of using these nucleic acid sequences and proteins in medical treatments and drug screening.
申请公布号 CA2259830(A1) 申请公布日期 2000.07.20
申请号 CA19992259830 申请日期 1999.01.20
申请人 HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP 发明人 PHAM, NAM;ROTIN, DANIELA
分类号 C07K14/47;C12N15/12;(IPC1-7):C12N15/12;A61K48/00;A61K38/17;C07K16/28;C07K16/32;A61K31/70;C07K14/705;C07K14/82 主分类号 C07K14/47
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