| 摘要 |
This invention relates to an electrophoresis separation medium having a gel matrix of at least one random, linear copolymer comprising a primary comonomer and at least one secondary comonomer. The primary comonomer is an acrylamide or an acrylamide derivative that provides the primary physical, chemical, and sieving properties of the gel matrix. The at least one secondary comonomer imparts an inherent physical, chemical, or sieving property to the copolymer chain. The desired properties incorporated by the secondary comonomer are hydrophilicity, hydrophobicity, copolymer chain stiffness, stability of copolymer entanglement structure, resistance to hydrolysis, processivity of copolymer chain extension, gel matrix viscosity, affinity of the copolymer to the surface of a supporting substrate, chirality, or a mixture thereof. The gel matrix has a viscosity of between about 1,500 to about 20,000 Cp, and between about 100,000 to 5,000,000 Daltons.
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