| 发明名称 |
ANTI-CCR4 ANTIBODIES AND METHODS OF USE THEREFOR |
| 摘要 |
The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 4 (CCR4) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR4 with a ligand thereof, and to use of the antibodies and fragments in research, therapeutic, prophylactic and diagnostic methods.
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| 申请公布号 |
WO0042074(A1) |
申请公布日期 |
2000.07.20 |
| 申请号 |
WO2000US00917 |
申请日期 |
2000.01.14 |
| 申请人 |
MILLENIUM PHARMACEUTICALS, INC.;WU, LIJUN;RUFFING, NANCY;ANDREW, DAVID |
发明人 |
WU, LIJUN;RUFFING, NANCY;ANDREW, DAVID |
| 分类号 |
G01N33/532;A61K39/395;A61P25/00;A61P43/00;C07K16/28;C12N5/10;C12N5/20;C12P21/08;G01N33/566;G01N33/577;(IPC1-7):C07K16/28;G01N33/68 |
主分类号 |
G01N33/532 |
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