| 摘要 |
organic chemistry, pharmacy. SUBSTANCE: invention relates to substituted phenylimidazolidines of the formula (I) where Y is O or NH; Z2 is CF3; Z1 is cyano- or nitro-radical; X is O or S; R3 is H or alkyl possibly substituted with halogen atom or cyano-radical R4, R5 is alkyl possibly substituted with hydroxy 1 that can be protected in all possible isomeric, racemic, enentiomeric and diasteriameric forms and acidic or basic salts that show anti-androgenic activity. EFFECT: improved method of synthesis, valuable pharmacological properties. 8 cl, 38 ex
|
