发明名称 |
METHODS OF SCREENING PROTEASE INHIBITORS, OF INDUCING MICE SUSCEPTIBLE TO HIV PROTEASE INHIBITOR-INDUCED DYSLIPIDEMIA, AND GENES ASSOCIATED THEREWITH |
摘要 |
The present invention relates generally to the side effects caused by retroviral therapies, including protease inhibitors, nucleoside reverse transcriptase inhibitors, and non-nucleoside reverse transcriptase inhibitors. Specifically, the present invention provides methods of screening a protease inhibitor for its capacity to affect symptoms or clinical conditions associated with lipodystrophy or dyslipidemia and related metabolic disorders, such as metabolic syndrome X, obesity, cardiovascular disorders, and impaired glucose tolerance in diabetes, in a patient.
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申请公布号 |
WO0042211(A1) |
申请公布日期 |
2000.07.20 |
申请号 |
WO2000US01205 |
申请日期 |
2000.01.19 |
申请人 |
GLAXO GROUP LIMITED;LENHARD, JAMES, MARTIN |
发明人 |
LENHARD, JAMES, MARTIN |
分类号 |
A01K67/027;A61K45/00;A61P1/02;A61P1/16;A61P3/00;A61P3/04;A61P3/10;A61P3/14;A61P5/14;A61P7/00;A61P9/10;A61P17/00;A61P17/14;A61P19/02;A61P21/00;C12N15/09;C12N15/85;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;(IPC1-7):C12Q1/00;C12N15/00;G01N33/00;A01K67/00 |
主分类号 |
A01K67/027 |
代理机构 |
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地址 |
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