发明名称 |
ASYMMETRIC SYNTHESIS OF BENZOXAZINONES |
摘要 |
<p>The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (VI-i) which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.</p> |
申请公布号 |
LV12432(B) |
申请公布日期 |
2000.07.20 |
申请号 |
LV19990000096 |
申请日期 |
1999.07.30 |
申请人 |
DUPONT PHARMACEUTICALS COMPANY |
发明人 |
PIERCE,MICHAEL ERNEST;CHOUDHURY,ANUSUYA;PARSONS,RODNEY LAWRENCE JR. |
分类号 |
A61K31/535;A61P31/18;A61P43/00;C07D265/18;(IPC1-7):C07D265/18 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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