发明名称 GRANULES FOR ORAL ADMINISTRATION, PROCESS FOR PRODUCING THE SAME, AND TABLETS PRODUCED FROM THE GRANULES
摘要 Granules and tablets for oral administration, containing angiotensin-converting enzyme inhibiting peptides and treated whey with a mixing fluid bed processor, wherein said whey is obtained from lactic acid fermentation liquid. The granules have properties of narrow particle distributions, low moisture absorption, and heavy specific gravity, as well as high free flowing. A process is also provided for producing the granules by the steps of: a) onto seed granules obtained in an earlier operation in a mixing fluid bed processor, spraying purified whey of lactic acid fermentation liquid to form preliminary granules; b) treating the preliminary granules thus obtained to reduce particle size in a size reduction mill; c) returning the treated powder to the mixing fluid bed processor, and, d) spraying additional purified whey onto the returned powder in the mixing fluid bed processor to form granules, while fluidizing the said powder.
申请公布号 WO0041677(A1) 申请公布日期 2000.07.20
申请号 WO2000JP00059 申请日期 2000.01.11
申请人 CALPIS CO., LTD 发明人 KITAMURA, SHUJI;UEYAMA, TAKASHI
分类号 A61J3/06;A61K9/16;A61K9/20;A61K31/00;A61K38/55;A61P9/00;A61P9/12;A61P43/00;(IPC1-7):A61K9/16;A61K38/06 主分类号 A61J3/06
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