| 摘要 |
A compound which comprises: (i) a saccharide compound having transglycosylase inhibitory activity; and (ii) a second compound that is capable of binding a protein or enzyme involved in cell wall biosynthesis, a precursor used in cell wall biosynthesis, the cell wall surface, or combinations thereof. The saccharide compound is linked directly or through a difunctional linker, to the non-saccharide compound; provided that: when the non-saccharide compound is a hexapeptide or a heptapeptide and the saccharide compound does not contain a phosphate or phosphonate ester, then the saccharide compound is not linked directly to the non-saccharide compound through a glycosidic linkage. The non-saccharide compound includes both "natural" (aglycones that are typically associated with a carbohydrate moiety) and "unnatural" (substances that are not typically associated with carbohydrate moiety) aglycones. Unnatural aglycones can be selected, for example, from peptide-binding dyes. |
