HUMANIZED ANTIBODY SPECIFIC FOR SURFACE ANTIGEN PRE-S1 OF HBV AND PREPARATION METHOD THEREOF
摘要
The present invention relates to humanized antibodies specific for HBV surface antigen pre-S1, which show binding affinity similar to mouse monoclonal antibody and which show remarkably reduced immunogenicity since they have less mouse-derived amino acid residues. Thus, the humanized antibodies of the present invention may be useful for the prevention of HBV infection and for the treatment of hepatitis B.
申请公布号
WO0031141(B1)
申请公布日期
2000.07.20
申请号
WO1999KR00699
申请日期
1999.11.19
申请人
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;KOREA GREEN CROSS CORPORATION;HONG, HYO, JEONG;RYU, CHUN, JEIH;HUR, HYANGSUK
