发明名称 |
Methods and compositions for inhibition of adaptor protein/tyrosine kinase interactions |
摘要 |
The present invention relates to methods and compositions for the inhibition of adaptor protein/protein tyrosine kinase protein interactions, especially wherein those interactions involving a protein tyrosine kinase capable of complexing with a member of the SH2- and/or SH3-containing family of adaptor proteins are associated with a cell proliferative disorder. Specifically, the present invention relates to particular compounds, especially quinazoline derivative compounds, and methods utilizing such compounds.
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申请公布号 |
US6090838(A) |
申请公布日期 |
2000.07.18 |
申请号 |
US19980090737 |
申请日期 |
1998.06.04 |
申请人 |
SUGEN, INC. |
发明人 |
TANG, PENG CHO;MCMAHON, GERALD;HARRIS, G. DAVIS |
分类号 |
A61K31/40;A61K31/403;A61K31/404;A61P35/00;C07D209/08;C07D209/14;(IPC1-7):C07D209/04 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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