发明名称 |
Processes and intermediates useful to make antifolates |
摘要 |
The present application relates to a series of novel sulfonic acid metal cation salts of the formula which are useful intermediates to prepare antifolate 5-substituted pyrrolo[2,3-d]pyrimidines. The present invention also relates to a novel process for preparing the sulfonic acid metal cation salts and to a novel process for preparing aldehydes of the formula from the corresponding sulfonic acid metal cation salts.
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申请公布号 |
US6090168(A) |
申请公布日期 |
2000.07.18 |
申请号 |
US19990413633 |
申请日期 |
1999.10.06 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
KJELL, DOUGLAS PATTON;SLATTERY, BRIAN JAMES;BARNETT, CHARLES JACKSON |
分类号 |
C07C67/313;(IPC1-7):C07D487/04;C07C69/76 |
主分类号 |
C07C67/313 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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