WATER-SOLUBLE DRUGS AND METHODS FOR THEIR PRODUCTION,申请号WO1999US16199-传众专利搜索

发明名称	WATER-SOLUBLE DRUGS AND METHODS FOR THEIR PRODUCTION
摘要	the present invention provides water-soluble drugs, in particular, water-soluble analogues of geldanamycin, and compositions comprising the same. This invention also provides a method of rendering water-insoluble drugs soluble in water through derivatization with a bifunctional linking molecule and subsequent conjugation to a polar moiety through a thio ether. The present invention further provides a method of treating cancer in a mammal.
申请公布号	WO0003737(A9)	申请公布日期	2000.07.13
申请号	WO1999US16199	申请日期	1999.07.15
申请人	THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;HO, DAVID, K.;MANDLER, RAYA;ALVARADO-LINDNER, ADA, BELINDA;UPADHYAY, KAYE, B., DILLAH;NEWMAN, DAVID, J.	发明人	HO, DAVID, K.;MANDLER, RAYA;ALVARADO-LINDNER, ADA, BELINDA;UPADHYAY, KAYE, B., DILLAH;NEWMAN, DAVID, J.
分类号	C07D225/06;A61K31/395;A61K45/00;A61K47/48;A61P35/00;C07D207/40;C07D207/416;C07D225/02;C07D403/12;(IPC1-7):A61K47/48	主分类号	C07D225/06
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