USE OF A RETINOID TYPE COMPOUND TO MODULATE IN VIVO THE DECOUPLING ACTIVITY OF THE PROTEIN UCP2

摘要

This invention relates to the use of a compound of the retinoid type particularly retinoic acid for the preparation of a medicament capable of modulating in vivo the decoupling activity of decoupling proteins. These compounds can be used conveniently for the treatment of diseases associated to an increase or reduction of the activity of decoupling proteins. According to a preferred embodiment, the retinoic acid will be used for the treatment of disease associated to a reduction of the decoupling activity of the protein UCP2 such as for example obesity.