| 发明名称 |
Inhibitors of alpha4beta1 mediated cell adhesion |
| 摘要 |
The present invention relates to small molecules according to formula (I) which are potent inhibitors of a alpha 4 beta 1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing alpha 4 beta 1 adhesion mediated conditions in a mammal such as a human. |
| 申请公布号 |
AU2209500(A) |
申请公布日期 |
2000.07.12 |
| 申请号 |
AU20000022095 |
申请日期 |
1999.12.20 |
| 申请人 |
TANABE SEIYAKU CO., LTD.;PHARMACIA & UPJOHN COMPANY |
发明人 |
BRADLEY R. TEEGARDEN;HONNAPPA JAYAKUMAR;KENJI MATSUKI;ROBERT A CHRUSCIEL;JED F. FISHER;STEVEN P. TANIS;EDWARD W. THOMAS;JAMES R. BLINN |
| 分类号 |
C07D295/04;A61K31/198;A61K31/22;A61K31/36;A61K31/401;A61K31/44;A61K31/445;A61K31/472;A61K31/5375;A61K38/00;A61P1/04;A61P9/10;A61P11/06;A61P17/06;A61P27/02;A61P29/00;A61P37/08;C07C233/87;C07C235/12;C07C235/20;C07C235/74;C07C235/78;C07C235/82;C07C235/84;C07C237/24;C07C237/36;C07C237/42;C07C255/31;C07C275/26;C07C275/42;C07C323/62;C07D207/16;C07D211/60;C07D211/62;C07D213/64;C07D213/65;C07D213/81;C07D213/82;C07D215/48;C07D217/16;C07D231/14;C07D237/14;C07D277/06;C07D295/215;C07D307/24;C07D307/71;C07D317/58;C07K5/02;C07K5/06;C07K5/065;C07K5/078;C07K5/097 |
主分类号 |
C07D295/04 |
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