发明名称 Rapamycin analogs containing tetrazol with shortened half-life
摘要 <p>A compound having formula (I) or a pharmaceutically acceptable salt or prodrug thereof, is an immunomodulatory agent and is useful in the treatment of restenosis and immune and autoimmune diseases. Also disclosed are cancer-, fungal growth-, restenosis-, post- transplant tissue rejection- and immune- and autoimmune disease-inhibiting compositions and a method of inhibiting cancer, fungal growth, restenosis, post- transplant tissue rejection, and immune and autoimmune disease in a mammal, with minimized side-effects due to shortened half-lives.</p>
申请公布号 CZ20001014(A3) 申请公布日期 2000.07.12
申请号 CZ20000001014 申请日期 1998.09.24
申请人 ABBOTT LABORATORIES 发明人 MOLLISON KARL W.
分类号 A61K31/395;A61K31/436;A61P9/00;A61P31/00;A61P31/10;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07D221/00;C07D273/00;C07D331/00;C07D498/08;C07D498/18;(IPC1-7):C07D498/08 主分类号 A61K31/395
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