| 摘要 |
This invention provides a novel G-protein coupled glycoprotein hormone receptor HG38, mutant and polymorphic forms of the receptor, nucleic acids encoding the same, expression vectors including the nucleic acids, host cells transformed with nucleic acids, transgenic knockout animals lacking the receptor and transgenic animals expressing a non-native receptor gene, antibodies against the receptor and polypeptides thereof and assays for modulators, agonists and antagonists of the receptor. The receptor proteins and polypeptides, nucleic acids, cells, animals and assays of this invention are useful in drug screening and development, diagnosis and therapeutic applications. |
