| 发明名称 |
GENE MUTATED IN COLORECTAL CANCER OF HUMANS |
| 摘要 |
<p>A new human gene termed MCC is disclosed. Methods, primers, probes and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expressed in most normal tissues. These results suggest that MCC is a tumor suppressor.</p> |
| 申请公布号 |
EP0580596(B1) |
申请公布日期 |
2000.07.12 |
| 申请号 |
EP19920905276 |
申请日期 |
1992.01.16 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY;THE UNIVERSITY OF UTAH;THE CANCER INSTITUTE OF JAPANESE FOUNDATION |
发明人 |
VOGELSTEIN, BERT;KINZLER, KENNETH, W.;WHITE, RAYMOND, L.;NAKAMURA, YUSUKE |
| 分类号 |
C07K16/00;C07K14/00;C07K14/47;C07K14/82;C07K16/30;C07K16/32;C12N15/09;C12N15/12;C12P21/08;C12Q1/68;G01N33/53;G01N33/574;(IPC1-7):C12Q1/68 |
主分类号 |
C07K16/00 |
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