发明名称 |
Receptor specific transepithelial transport of immunogens |
摘要 |
Methods and products for modulating an immune response are provided. Pharmaceutical preparations contain a conjugate of an antigen and a FcRn binding partner. The conjugates are administered to mammals in effective amounts to modulate the immune system by stimulating the immune response against the antigen or tolerizing the immune system to the antigen. The antigen may be characteristic of a pathogen, of an autoimmune disease or of an allergen.
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申请公布号 |
US6086875(A) |
申请公布日期 |
2000.07.11 |
申请号 |
US19950374159 |
申请日期 |
1995.01.17 |
申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;BRANDEIS UNIVERSITY |
发明人 |
BLUMBERG, RICHARD S.;SIMISTER, NEIL E.;LENCER, WAYNE L. |
分类号 |
A61K39/385;A61K47/48;A61P37/02;C07K16/00;(IPC1-7):A61K39/385;A61K39/44 |
主分类号 |
A61K39/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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