发明名称 HEPATIC FIBROGENETIC INHIBITOR
摘要 PROBLEM TO BE SOLVED: To obtain the subject inhibitor having significant proliferation inhibitory effect against hepatic Ito cells and protein formation inhibitory effect by including crude-drug Scutellarial Radix-derived flavonoid compound(s). SOLUTION: This inhibitor contains at least one kind of crude-drug Scutellarial Radix-derived flavonoid compound (e.g. Baicalein of formula I, Baicalin of formula II, Wogonin of formula III, Wogonoside of formula IV). The inhibitor is pref. if the form of a crude drug, inhibiting hepatic fibrogenesis in chronic hepatopathy involving fibrosis such as chronic hepatitis, its daily dose being 1-2,000 mg/kg, pref. 1-1,000 mg/kg or so.
申请公布号 JP2000191544(A) 申请公布日期 2000.07.11
申请号 JP19980372842 申请日期 1998.12.28
申请人 JAPAN SCIENCE & TECHNOLOGY CORP 发明人 INOUE TOMOO
分类号 C07H17/07;A61K31/00;A61K31/35;A61K31/352;A61K31/353;A61K31/70;A61K31/7042;A61K31/7048;A61K36/53;A61P1/00;A61P1/16;A61P43/00;C07D311/30 主分类号 C07H17/07
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